Methotrexate-gamma-aspartate
| Code | Size | Price |
|---|
| TAR-T24457-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24457-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24457-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.
CAS:
64801-58-7
Formula:
C24H27N9O8
Molecular Weight:
569.535
Purity:
0.98
SMILES:
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=O)N[C@@H](CC(O)=O)C(O)=O)C(O)=O
References
1. Amin K, Ng KY, Brown CS, Bruno MS, Heath TD. LDL induced association of anionic liposomes with cells and delivery of contents as shown by the increase in potency of liposome dependent drugs. Pharm Res. 2001 Jul;18(7):914-21. PubMed PMID: 11496949.
2. Comiskey SJ, Heath TD. Leakage and delivery of liposome-encapsulated methotrexate-gamma-aspartate in a chemically defined medium. Biochim Biophys Acta. 1990 May 24;1024(2):307-17. PubMed PMID: 2354182.
3. Comiskey SJ, Heath TD. Serum-induced leakage of negatively charged liposomes at nanomolar lipid concentrations. Biochemistry. 1990 Apr 17;29(15):3626-31. PubMed PMID: 2340262.
4. Hege KM, Daleke DL, Waldmann TA, Matthay KK. Comparison of anti-Tac and anti-transferrin receptor-conjugated liposomes for specific drug delivery to adult T-cell leukemia. Blood. 1989 Nov 1;74(6):2043-52. PubMed PMID: 2679914.