Methyl acetimidate

TargetMol
Product Code: TAR-T24458
Supplier: TargetMol
CodeSizePrice
TAR-T24458-5mg5mg£850.00
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Quantity:
TAR-T24458-50mg50mg£1,661.00
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Quantity:
TAR-T24458-100mg100mg£2,079.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Methyl acetimidate is an effective in vitro antisickling agent. It has few detrimental effects on the red cell.
CAS:
14777-29-8
Formula:
C3H7NO
Molecular Weight:
73.095
Purity:
0.98
SMILES:
COC(C)=N

References

1. Chao TL, Berenfeld MR. Prevention of the immune agglutination of methyl acetimidate-reacted sickle erythrocytes by prior reaction with pyridoxal 5'-phosphate. J Biol Chem. 1981 Jun 10;256(11):5324-6. PubMed PMID: 7240139. 2. Chao TL, Berenfeld MR, Gabuzda TG. Current status of methyl acetimidate as an extracorporeal antisickling agent. Am J Pediatr Hematol Oncol. 1984 Spring;6(1):55-8. PubMed PMID: 6711765. 3. Richardson VB, Littlefield LG, Colyer SP. Cytogenetic evaluations in human lymphocytes exposed to methyl acetimidate, a lysine-specific protein crosslinking agent. Mutat Res. 1987 Sep;180(1):121-9. PubMed PMID: 3114624. 4. Chao TL, Berenfeld MR, Gabuzda TG. Protection of erythrocyte membrane amino groups from reaction with methyl acetimidate by pyridoxal 5'-phosphate Schiff base formation. Biochim Biophys Acta. 1984 Apr 11;771(2):183-7. PubMed PMID: 6704394.