myomiR-IN-1
Code | Size | Price |
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TAR-T24512-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24512-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24512-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
myomiR-IN-1 is a myomiRs inhibitor that acts by inhibiting the translation of myoD in C2C12 cells without changing the expression level of myoD mRNA and downregulating the expression of differentiation markers.
CAS:
1392224-59-7
Formula:
C33H27NO6
Molecular Weight:
533.58
Purity:
0.98
SMILES:
COC12C(C(=C1c1ccc(OC(=O)OC(C)(C)C)c3ncccc13)c1ccccc1)C(=O)c1ccccc1C2=O
References
1. Graham ZA, De Gasperi R, Bauman WA, Cardozo CP. Recombinant myostatin reduces highly expressed microRNAs in differentiating C2C12 cells. Biochem Biophys Rep. 2017 Mar;9:273-280. PubMed PMID: 28691106; PubMed Central PMCID: PMC5500170.
2. Tan SB, Li J, Chen X, Zhang W, Zhang D, Zhang C, Li D, Zhang Y. Small molecule inhibitor of myogenic microRNAs leads to a discovery of miR-221/222-myoD-myomiRs regulatory pathway. Chem Biol. 2014 Oct 23;21(10):1265-1270. doi: 10.1016/j.chembiol.2014.06.011. Epub 2014 Sep 18. PubMed PMID: 25242288.