NIC
| Code | Size | Price |
|---|
| TAR-T24531-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24531-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24531-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
NIC is an inhibitor of host invasion. It is also an inhibitor of VEGF binding to immobilized heparin.
CAS:
114773-20-5
Formula:
C15H16ClN3O3
Molecular Weight:
321.76
Purity:
0.98
SMILES:
CCCCc1nc(Cl)c(C=O)n1Cc1ccc(cc1)[N+]([O-])=O
References
1. Liu X, Lu L, Liu X, Pan C, Feng E, Wang D, Zhu L, Wang H. Comparative proteomics of Shigella flexneri 2a strain 301 using a rabbit ileal loop model reveals key proteins for bacterial adaptation in host niches. Int J Infect Dis. 2015 Nov;40:28-33. doi: 10.1016/j.ijid.2015.09.014. Epub 2015 Sep 28. PubMed PMID: 26417879.
2. Yang G, Wang L, Wang Y, Li P, Zhu J, Qiu S, Hao R, Wu Z, Li W, Song H. hfq regulates acid tolerance and virulence by responding to acid stress in Shigella flexneri. Res Microbiol. 2015 Jul-Aug;166(6):476-85. doi: 10.1016/j.resmic.2015.06.007. Epub 2015 Jun 24. PubMed PMID: 26117597.
3. Chandramohanadas R, Basappa, Russell B, Liew K, Yau YH, Chong A, Liu M, Gunalan K, Raman R, Renia L, Nosten F, Shochat SG, Dao M, Sasisekharan R, Suresh S, Preiser P. Small molecule targeting malaria merozoite surface protein-1 (MSP-1) prevents host invasion of divergent plasmodial species. J Infect Dis. 2014 Nov 15;210(10):1616-26. doi: 10.1093/infdis/jiu296. Epub 2014 May 26. PubMed PMID: 24864124; PubMed Central PMCID: PMC4334792.
4. Sheokand S, Brewin NJ. Cysteine proteases in nodulation and nitrogen fixation. Indian J Exp Biol. 2003 Oct;41(10):1124-32. Review. PubMed PMID: 15242278.