nNOS-IN-25
| Code | Size | Price |
|---|
| TAR-T24539-5mg | 5mg | £1,412.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24539-50mg | 50mg | £2,785.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24539-100mg | 100mg | £3,765.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
nNOS-IN-25 is an effective, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase.
CAS:
1895092-16-6
Formula:
C21H22N4
Molecular Weight:
330.435
Purity:
0.98
SMILES:
Cc1cc(CCNCc2ccc3c(C)cc(N)nc3c2)ccc1C#N
References
1. Wu QQ, Xiao Y, Duan MX, Yuan Y, Jiang XH, Yang Z, Liao HH, Deng W, Tang QZ. Aucubin protects against pressure overload-induced cardiac remodelling via ?3-AR-nNOS cascades. Br J Pharmacol. 2018 Feb 15. doi: 10.1111/bph.14164. [Epub ahead of print] PubMed PMID: 29447430.
2. Singh VK, Lal B. Nitric oxide (NO) stimulates steroidogenesis and folliculogenesis in fish. Reproduction. 2017 Feb;153(2):133-146. Epub 2016 Nov 4. PubMed PMID: 27815560.
3. Leger PL, Bonnin P, Moretti R, Tanaka S, Duranteau J, Renolleau S, Baud O, Charriaut-Marlangue C. Early Recruitment of Cerebral Microcirculation by Neuronal Nitric Oxide Synthase Inhibition in a Juvenile Ischemic Rat Model. Cerebrovasc Dis. 2016;41(1-2):40-9. doi: 10.1159/000441663. Epub 2015 Nov 25. PubMed PMID: 26599266.
4. Vitcheva V, Simeonova R, Kondeva-Burdina M, Mitcheva M. Selective Nitric Oxide Synthase Inhibitor 7-Nitroindazole Protects against Cocaine-Induced Oxidative Stress in Rat Brain. Oxid Med Cell Longev. 2015;2015:157876. doi: 10.1155/2015/157876. Epub 2015 Oct 20. PubMed PMID: 26576217; PubMed Central PMCID: PMC4630414.