NSC-639829
| Code | Size | Price |
|---|
| TAR-T24553-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24553-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24553-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
NSC-639829 is a tubulin polymerization inhibitor that acts by demonstrating potent antitumor activities against several cancer cell lines.
CAS:
134742-19-1
Formula:
C21H20BrN5O3
Molecular Weight:
470.327
Purity:
0.98
SMILES:
CN(C)c1ccccc1C(=O)NC(=O)Nc1ccc(Oc2ncc(Br)cn2)c(C)c1
References
1. Balcer-Kubiczek EK, Attarpour M, Edelman MJ. The synergistic effect of dimethylamino benzoylphenylurea (NSC #639829) and X-irradiation on human lung carcinoma cell lines. Cancer Chemother Pharmacol. 2007 May;59(6):781-7. Epub 2006 Sep 7. PubMed PMID: 16957930.
2. Rao VM, Nerurkar M, Pinnamaneni S, Rinaldi F, Raghavan K. Co-solubilization of poorly soluble drugs by micellization and complexation. Int J Pharm. 2006 Aug 17;319(1-2):98-106. Epub 2006 Apr 7. PubMed PMID: 16765542.
3. Hallur G, Jimeno A, Dalrymple S, Zhu T, Jung MK, Hidalgo M, Isaacs JT, Sukumar S, Hamel E, Khan SR. Benzoylphenylurea sulfur analogues with potent antitumor activity. J Med Chem. 2006 Apr 6;49(7):2357-60. PubMed PMID: 16570932.
4. Jain A, Sanghvi T, Yalkowsky SH. Liposome formulation of NSC-639829 using halothane as a solvent: a technical note. AAPS PharmSciTech. 2003 Oct 15;4(4):E52. PubMed PMID: 15198547; PubMed Central PMCID: PMC2750645.