PARPi-FL
| Code | Size | Price |
|---|
| TAR-T24597-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
PARPi-FL is an agent of fluorescent PARP imaging. In vitro, it is capable of detecting the target engagement of a PARP inhibitor panel.
CAS:
1380359-84-1
Formula:
C34H32BF3N6O3
Molecular Weight:
640.47
Purity:
0.98
SMILES:
CC1=CC(C)=[N+]2C1=Cc1ccc(CCC(=O)N3CCN(CC3)C(=O)c3cc(Cc4n[nH]c(=O)c5ccccc45)ccc3F)n1[B-]2(F)F
References
1. Zhang J. Poly (ADP-ribose) polymerase inhibitor: an evolving paradigm in the treatment of prostate cancer. Asian J Androl. 2014 May-Jun;16(3):401-6. doi: 10.4103/1008-682X.123684. Review. PubMed PMID: 24589464; PubMed Central PMCID: PMC4023365.
2. Shackelford RE, Mayhall K, Maxwell NM, Kandil E, Coppola D. Nicotinamide phosphoribosyltransferase in malignancy: a review. Genes Cancer. 2013 Nov;4(11-12):447-56. doi: 10.1177/1947601913507576. Review. PubMed PMID: 24386506; PubMed Central PMCID: PMC3877665.
3. Mason KA, Raju U, Buchholz TA, Wang L, Milas ZL, Milas L. Poly (ADP-ribose) polymerase inhibitors in cancer treatment. Am J Clin Oncol. 2014 Feb;37(1):90-100. doi: 10.1097/COC.0b013e3182467dce. Review. PubMed PMID: 22495455.
4. Ismail-Khan R, Bui MM. A review of triple-negative breast cancer. Cancer Control. 2010 Jul;17(3):173-6. Review. PubMed PMID: 20664514.