Phostriecin
| Code | Size | Price |
|---|
| TAR-T24636-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Fostriecin is an antifungal and antitumor antibiotic.
CAS:
131774-59-9
Formula:
C23H34O8S
Molecular Weight:
470.58
Purity:
0.98
SMILES:
CCCCCC=CC=CC=CC(O)C(C)C(CC=CC1OC(=O)C=CC1O)OS(O)(=O)=O
References
1. Tanaka H, Kageyama K, Yoshimura N, Asada R, Kusumoto K, Miwa N. Anti-tumor and anti-invasive effects of diverse delta-alkyllactones: dependence on molecular side-chain length, action period and intracellular uptake. Life Sci. 2007 Apr 24;80(20):1851-5. Epub 2007 Feb 27. PubMed PMID: 17382354.
2. Burke CP, Swingle MR, Honkanen RE, Boger DL. Total synthesis and evaluation of phostriecin and key structural analogues. J Org Chem. 2010 Nov 19;75(22):7505-13. doi: 10.1021/jo1010203. Epub 2010 Jul 29. PubMed PMID: 20669916; PubMed Central PMCID: PMC2978778.
3. Burke CP, Haq N, Boger DL. Total synthesis, assignment of the relative and absolute stereochemistry, and structural reassignment of phostriecin (aka Sultriecin). J Am Chem Soc. 2010 Feb 24;132(7):2157-9. doi: 10.1021/ja9097252. PubMed PMID: 20108904; PubMed Central PMCID: PMC2824046.
4. Ohkuma H, Naruse N, Nishiyama Y, Tsuno T, Hoshino Y, Sawada Y, Konishi M, Oki T. Sultriecin, a new antifungal and antitumor antibiotic from Streptomyces roseiscleroticus. Production, isolation, structure and biological activity. J Antibiot (Tokyo). 1992 Aug;45(8):1239-49. PubMed PMID: 1399844.