PI3K inhibitor C 96

TargetMol
Product Code: TAR-T24637
Supplier: TargetMol
CodeSizePrice
TAR-T24637-5mg5mg£850.00
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Quantity:
TAR-T24637-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24637-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.
CAS:
1502813-63-9
Formula:
C11H8N2O3S
Molecular Weight:
248.26
Purity:
0.98
SMILES:
O=C1NC(=O)C(=CC=Cc2cccs2)C(=O)N1

References

1. Naderi R, Esmaeili-Mahani S, Abbasnejad M. Phosphatidylinositol-3-kinase and protein kinase C are involved in the pro-cognitive and anti-anxiety effects of phytohormone abscisic acid in rats. Biomed Pharmacother. 2017 Dec;96:112-119. doi: 10.1016/j.biopha.2017.09.089. Epub 2017 Sep 29. PubMed PMID: 28968539. 2. Lim W, Bae H, Bazer FW, Song G. Stimulatory effects of fibroblast growth factor 2 on proliferation and migration of uterine luminal epithelial cells during early pregnancy. Biol Reprod. 2017 Jan 1;96(1):185-198. doi: 10.1095/biolreprod.116.142331. PubMed PMID: 28395342. 3. Previs RA, Armaiz-Pena GN, Ivan C, Dalton HJ, Rupaimoole R, Hansen JM, Lyons Y, Huang J, Haemmerle M, Wagner MJ, Gharpure KM, Nagaraja AS, Filant J, McGuire MH, Noh K, Dorniak PL, Linesch SL, Mangala LS, Pradeep S, Wu SY, Sood AK. Role of YAP1 as a Marker of Sensitivity to Dual AKT and P70S6K Inhibition in Ovarian and Uterine Malignancies. J Natl Cancer Inst. 2017 Jul 1;109(7). doi: 10.1093/jnci/djw296. PubMed PMID: 28376174. 4. Gu SH, Hsieh YC, Lin PL. Signaling involved in PTTH-stimulated 4E-BP phosphorylation in prothoracic gland cells of Bombyx mori. J Insect Physiol. 2017 Jan;96:1-8. doi: 10.1016/j.jinsphys.2016.10.007. Epub 2016 Oct 14. PubMed PMID: 27751888.