PPTN Mesylate

TargetMol
Product Code: TAR-T24655
Supplier: TargetMol
CodeSizePrice
TAR-T24655-5mg5mg£850.00
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Quantity:
TAR-T24655-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24655-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
PPTN Mesylate is an effective and highly selective antagonist of the P2Y14 receptor.
CAS:
1160271-31-7
Formula:
C30H28F3NO5S
Molecular Weight:
571.61
Purity:
0.98
SMILES:
CS(O)(=O)=O.OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F

References

1. de Oliveira RC, de Oliveira R, Falconi-Sobrinho LL, Biagioni AF, Almada RC, Dos Anjos-Garcia T, Bazaglia-de-Sousa G, Khan AU, Coimbra NC. Neurotoxic lesions of the pedunculopontine tegmental nucleus impair the elaboration of postictal antinociception. Physiol Behav. 2018 May 12. pii: S0031-9384(18)30234-8. doi: 10.1016/j.physbeh.2018.05.011. [Epub ahead of print] PubMed PMID: 29763677. 2. Rafehi M, M?ller CE. Tools and drugs for uracil nucleotide-activated P2Y receptors. Pharmacol Ther. 2018 Apr 13. pii: S0163-7258(18)30065-2. doi: 10.1016/j.pharmthera.2018.04.002. [Epub ahead of print] Review. PubMed PMID: 29660366. 3. V?zquez-Delgado E, Viaplana-Guti?rrez M, Figueiredo R, Renton T, Gay-Escoda C, Valmaseda-Castell?n E. Prevalence of neuropathic pain and sensory alterations after dental implant placement in a university-based oral surgery department: A retrospective cohort study. Gerodontology. 2018 Jun;35(2):117-122. doi: 10.1111/ger.12326. Epub 2018 Feb 19. PubMed PMID: 29460459. 4. Abbas ZSB, Latif ML, Dovlatova N, Fox SC, Heptinstall S, Dunn WR, Ralevic V. UDP-sugars activate P2Y(14) receptors to mediate vasoconstriction of the porcine coronary artery. Vascul Pharmacol. 2018 Apr;103-105:36-46. doi: 10.1016/j.vph.2017.12.063. Epub 2017 Dec 15. PubMed PMID: 29253618; PubMed Central PMCID: PMC5906693.