S-1360
Code | Size | Price |
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TAR-T24752-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24752-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24752-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
S-1360 is an inhibitor of HIV-1 integrase.
CAS:
280571-30-4
Formula:
C16H12FN3O3
Molecular Weight:
313.288
Purity:
0.98
SMILES:
OC(=C/C(=O)c1ccc(Cc2ccc(F)cc2)o1)c1ncn[nH]1
References
1. Kashyap T, Germain E, Roche M, Lyle S, Rabinovitz I. Role of ?4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration. Lab Invest. 2011 Oct;91(10):1414-26. doi: 10.1038/labinvest.2011.104. Epub 2011 Jul 18. PubMed PMID: 21769085; PubMed Central PMCID: PMC3184203.
2. Huang M, Grant GH, Richards WG. Binding modes of diketo-acid inhibitors of HIV-1 integrase: a comparative molecular dynamics simulation study. J Mol Graph Model. 2011 Jun;29(7):956-64. doi: 10.1016/j.jmgm.2011.04.002. Epub 2011 Apr 9. PubMed PMID: 21531158; PubMed Central PMCID: PMC3101338.
3. Bacchi A, Carcelli M, Compari C, Fisicaro E, Pala N, Rispoli G, Rogolino D, Sanchez TW, Sechi M, Neamati N. HIV-1 IN strand transfer chelating inhibitors: a focus on metal binding. Mol Pharm. 2011 Apr 4;8(2):507-19. doi: 10.1021/mp100343x. Epub 2011 Mar 8. PubMed PMID: 21323359.
4. Barreca ML, Iraci N, De Luca L, Chimirri A. Induced-fit docking approach provides insight into the binding mode and mechanism of action of HIV-1 integrase inhibitors. ChemMedChem. 2009 Sep;4(9):1446-56. doi: 10.1002/cmdc.200900166. PubMed PMID: 19544345.