SD-1029
| Code | Size | Price |
|---|
| TAR-T24774-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24774-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24774-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
SD-1029 is a cell-permeable JAK2 inhibitor.
CAS:
118372-34-2
Formula:
C25H32Br2Cl2N2O3
Molecular Weight:
639.25
Purity:
0.98
SMILES:
Br.Br.CN(C)CC1CCC2=C(C(C3=C(CCC(CN(C)C)C3=O)O2)c2ccc(Cl)c(Cl)c2)C1=O
References
1. Zelano J, Larsson D, Kumlien E, ?sberg S. Pre-stroke seizures: A nationwide register-based investigation. Seizure. 2017 Jul;49:25-29. doi: 10.1016/j.seizure.2017.05.010. Epub 2017 May 17. PubMed PMID: 28544888.
2. Jiang X, Kanda T, Wu S, Nakamoto S, Saito K, Shirasawa H, Kiyohara T, Ishii K, Wakita T, Okamoto H, Yokosuka O. Suppression of La antigen exerts potential antiviral effects against hepatitis A virus. PLoS One. 2014 Jul 7;9(7):e101993. doi: 10.1371/journal.pone.0101993. eCollection 2014. PubMed PMID: 24999657; PubMed Central PMCID: PMC4084951.
3. Liu Y, Liu A, Xu Z, Yu W, Wang H, Li C, Lin J. XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. Apoptosis. 2011 May;16(5):502-10. doi: 10.1007/s10495-011-0578-0. PubMed PMID: 21311975.
4. Che Mat NF, Zhang X, Guzzo C, Gee K. Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus kinase/signal transducer and activation of transcription pathway in human CD4?T cells. J Interferon Cytokine Res. 2011 Apr;31(4):363-71. doi: 10.1089/jir.2010.0083. Epub 2010 Dec 7. PubMed PMID: 21138378.