STS-E412
Code | Size | Price |
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TAR-T24840-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24840-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24840-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
STS-E412 is a selective activator of the tissue-protective EPOR/CD131 receptor.
CAS:
1609980-39-3
Formula:
C15H15ClN4O2
Molecular Weight:
318.76
Purity:
0.98
SMILES:
Cc1cc(C)n2nc(OCCOc3ccc(Cl)cc3)nc2n1
References
1. Miller JL, Rai M, Frigon NL, Pandolfo M, Punnonen J, Spencer JR. Erythropoietin and small molecule agonists of the tissue-protective erythropoietin receptor increase FXN expression in neuronal cells in vitro and in Fxn-deficient KIKO mice in vivo. Neuropharmacology. 2017 Sep 1;123:34-45. doi: 10.1016/j.neuropharm.2017.05.011. Epub 2017 May 11. PubMed PMID: 28504123.
2. Miller JL, Church TJ, Leonoudakis D, Lariosa-Willingham K, Frigon NL, Tettenborn CS, Spencer JR, Punnonen J. Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor. Mol Pharmacol. 2015 Aug;88(2):357-67. doi: 10.1124/mol.115.098400. Epub 2015 May 27. PubMed PMID: 26018904; PubMed Central PMCID: PMC4518087.