Tedisamil
| Code | Size | Price |
|---|
| TAR-T24863-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24863-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24863-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tedisamil is a blocker of K+ currents in cardiac tissues, exerts bradycardic effects. It is an antiarrhythmic drug with predominantly class III activity. It has shown clinical efficacy in angina pectoris.
CAS:
90961-53-8
Formula:
C19H32N2
Molecular Weight:
288.479
Purity:
0.98
SMILES:
C(C1CC1)N1CC2CN(CC3CC3)CC(C1)C21CCCC1
References
1. D?molis JL, Martel C, Funck-Brentano C, Sachse A, Weimann HJ, Jaillon P. Effects of tedisamil, atenolol and their combination on heart and rate-dependent QT interval in healthy volunteers. Br J Clin Pharmacol. 1997 Oct;44(4):403-9. PubMed PMID: 9354317; PubMed Central PMCID: PMC2042860.
2. Hohnloser SH, Dorian P, Straub M, Beckmann K, Kowey P. Safety and efficacy of intravenously administered tedisamil for rapid conversion of recent-onset atrial fibrillation or atrial flutter. J Am Coll Cardiol. 2004 Jul 7;44(1):99-104. PubMed PMID: 15234416.
3. van Haarst AD, Dijkmans AC, Weimann HJ, Kemme MJ, Bosch JJ, Schoemaker RC, Cohen AF, Burggraaf J. Clinically important interaction between tedisamil and verapamil. J Clin Pharmacol. 2009 May;49(5):560-7. doi: 10.1177/0091270009332812. Epub 2009 Mar 19. PubMed PMID: 19299533.
4. Mitrovic V, Miskovic A, Strau M, Thormann J, Pitschner H, Hamm C. Hemodynamic, antiischemic, and neurohumoral effects of tedisamil and atenolol in patients with coronary artery disease. Cardiovasc Drugs Ther. 2000 Oct;14(5):511-21. PubMed PMID: 11101199.