TRP-601
| Code | Size | Price |
|---|
| TAR-T24903-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
TRP-601 is a caspase inhibitor.
CAS:
1094569-02-4
Formula:
C40H48F2N6O11
Molecular Weight:
826.852
Purity:
0.98
SMILES:
COC(=O)C[C@H](NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N([C@@H](C)C(N)=O)C(CC(=O)OC)C(=O)COc1c(F)cccc1F
References
1. Sifringer M, Bendix I, B?rner C, Endesfelder S, von Haefen C, Kalb A, Holifanjaniaina S, Prager S, Schlager GW, Keller M, Jacotot E, Felderhoff-Mueser U. Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis. Cell Death Dis. 2012 Jan 12;3:e250. doi: 10.1038/cddis.2011.133. PubMed PMID: 22237207; PubMed Central PMCID: PMC3270267.
2. Chauvier D, Renolleau S, Holifanjaniaina S, Ankri S, Bezault M, Schwendimann L, Rousset C, Casimir R, Hoebeke J, Smirnova M, Debret G, Trichet AP, Carlsson Y, Wang X, Bernard E, H?bert M, Rauzier JM, Matecki S, Lacampagne A, Rustin P, Mariani J, Hagberg H, Gressens P, Charriaut-Marlangue C, Jacotot E. Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor. Cell Death Dis. 2011 Sep 1;2:e203. doi: 10.1038/cddis.2011.87. PubMed PMID: 21881605; PubMed Central PMCID: PMC3186905.