Tyrphostin 51
| Code | Size | Price |
|---|
| TAR-T24909-5mg | 5mg | £414.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24909-50mg | 50mg | £1,412.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24909-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tyrphostin 51 is an effective inhibitor of EGFR kinase.
CAS:
126433-07-6
Formula:
C13H8N4O3
Molecular Weight:
268.232
Purity:
0.98
SMILES:
NC(C(=Cc1cc(O)c(O)c(O)c1)C#N)=C(C#N)C#N
References
1. Chung FY, Song HJ, Park SY, Jang HS, Kim DS, Sim SS, Sohn UD. Signaling mechanisms of sphingosine 1-phosphate-induced ERK1/2 activation in cultured feline esophageal smooth muscle cells. Arch Pharm Res. 2008 Nov;31(11):1437-45. doi: 10.1007/s12272-001-2128-8. Epub 2008 Nov 21. PubMed PMID: 19023540.
2. Ikeda M, Gunji Y, Sonoda H, Oshikawa S, Shimono M, Horie A, Ito K, Yamasaki S. Inhibitory effect of tyrphostin 47 on Shiga toxin-induced cell death. Eur J Pharmacol. 2006 Sep 28;546(1-3):36-9. Epub 2006 Jul 26. PubMed PMID: 16919262.
3. Lee TS, Song HJ, Jeong JH, Min YS, Shin CY, Sohn UD. IL-1beta activates p44/42 and p38 mitogen-activated protein kinases via different pathways in cat esophageal smooth muscle cells. World J Gastroenterol. 2006 Feb 7;12(5):716-22. PubMed PMID: 16521184; PubMed Central PMCID: PMC4066121.
4. Khan SM, Oliver RH, Yeh J. Epidermal growth factor receptor inhibition by tyrphostin 51 induces apoptosis in luteinized granulosa cells. J Clin Endocrinol Metab. 2005 Jan;90(1):469-73. Epub 2004 Oct 19. PubMed PMID: 15494464.