VU625
| Code | Size | Price |
|---|
| TAR-T24948-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24948-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24948-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
VU625 is an effective inhibitor of Aedes aegypti inward rectifier potassium channels.
CAS:
901008-62-6
Formula:
C19H22N2O4S
Molecular Weight:
374.46
Purity:
0.98
SMILES:
CCC(=O)N1C(C)Cc2cc(ccc12)S(=O)(=O)Nc1cccc(OC)c1
References
1. Beyenbach KW, Yu Y, Piermarini PM, Denton J. Targeting renal epithelial channels for the control of insect vectors. Tissue Barriers. 2015 Sep 1;3(4):e1081861. doi: 10.1080/21688370.2015.1081861. eCollection 2015 Oct-Dec. Review. PubMed PMID: 26716074; PubMed Central PMCID: PMC4681290.
2. Piermarini PM, Dunemann SM, Rouhier MF, Calkins TL, Raphemot R, Denton JS, Hine RM, Beyenbach KW. Localization and role of inward rectifier K(+) channels in Malpighian tubules of the yellow fever mosquito Aedes aegypti. Insect Biochem Mol Biol. 2015 Dec;67:59-73. doi: 10.1016/j.ibmb.2015.06.006. Epub 2015 Jun 12. PubMed PMID: 26079629.
3. Raphemot R, Rouhier MF, Swale DR, Days E, Weaver CD, Lovell KM, Konkel LC, Engers DW, Bollinger SR, Hopkins C, Piermarini PM, Denton JS. Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels. PLoS One. 2014 Nov 6;9(11):e110772. doi: 10.1371/journal.pone.0110772. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0119883. Bollinger, Sean F [corrected to Bollinger, Sean R]. PubMed PMID: 25375326; PubMed Central PMCID: PMC4222822.