10-Formylfolic acid

TargetMol
Product Code: TAR-T24962
Supplier: TargetMol
CodeSizePrice
TAR-T24962-5mg5mg£1,167.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
10-Formylfolic acid is a potent dihydrofolate reductase inhibitor.
CAS:
134-05-4
Formula:
C20H19N7O7
Molecular Weight:
469.414
Purity:
0.98
SMILES:
Nc1nc(=O)c2nc(CN(C=O)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2[nH]1

References

1. Ashokkumar K, Sivakumar P, Saradhadevi M. Identification and determination of naturally occurring folates in grains of rice (Oryza sativa L.) by UPLC-MS/MS analysis. Nat Prod Res. 2018 Jul;32(14):1733-1737. doi: 10.1080/14786419.2017.1392957. Epub 2017 Oct 23. PubMed PMID: 29058482. 2. Kopp M, Morisset R, Rychlik M. Characterization and Interrelations of One-Carbon Metabolites in Tissues, Erythrocytes, and Plasma in Mice with Dietary Induced Folate Deficiency. Nutrients. 2017 May 5;9(5). pii: E462. doi: 10.3390/nu9050462. PubMed PMID: 28475162; PubMed Central PMCID: PMC5452192. 3. Kopp M, D?rr K, Steigleder M, Clavel T, Rychlik M. Development of stable isotope dilution assays for the quantitation of intra- and extracellular folate patterns of Bifidobacterium adolescentis. J Chromatogr A. 2016 Oct 21;1469:48-59. doi: 10.1016/j.chroma.2016.09.048. Epub 2016 Sep 22. PubMed PMID: 27692648. 4. Kopp M, Morisset R, Koehler P, Rychlik M. Stable Isotope Dilution Assays for Clinical Analyses of Folates and Other One-Carbon Metabolites: Application to Folate-Deficiency Studies. PLoS One. 2016 Jun 8;11(6):e0156610. doi: 10.1371/journal.pone.0156610. eCollection 2016. PubMed PMID: 27276031; PubMed Central PMCID: PMC4898732.