11-Deazahomofolic acid

TargetMol
Product Code: TAR-T24965
Supplier: TargetMol
CodeSizePrice
TAR-T24965-5mg5mg£850.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
11-Deazahomofolic acid is a phosphoribosylglycinamide formyltransferase inhibitor.
CAS:
119770-54-6
Formula:
C21H22N6O6
Molecular Weight:
454.443
Purity:
0.98
SMILES:
Nc1nc(=O)c2nc(CCCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2[nH]1

References

1. Nair MG, Murthy BR, Patil SD, Kisliuk RL, Thorndike J, Gaumont Y, Ferone R, Duch DS, Edelstein MP. Folate analogues. 31. Synthesis of the reduced derivatives of 11-deazahomofolic acid, 10-methyl-11-deazahomofolic acid, and their evaluation as inhibitors of glycinamide ribonucleotide formyltransferase. J Med Chem. 1989 Jun;32(6):1277-83. PubMed PMID: 2498518.