TargetMol

AK 275

Product Code:
 
TAR-T25009
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25009-5mg5mg£850.00
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Quantity:
TAR-T25009-50mg50mg£1,661.00
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Quantity:
TAR-T25009-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro.
CAS:
158798-83-5
Formula:
C20H31N3O4
Molecular Weight:
377.485
Purity:
0.98
SMILES:
CCC(N)C(=O)N(CC)C(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

References

1. James T, Matzelle D, Bartus R, Hogan EL, Banik NL. New inhibitors of calpain prevent degradation of cytoskeletal and myelin proteins in spinal cord in vitro. J Neurosci Res. 1998 Jan 15;51(2):218-22. PubMed PMID: 9469575. 2. Zalewska T. Calpain as proposed target for neuroprotective treatment of brain ischemia. Folia Neuropathol. 1996;34(3):121-7. Review. PubMed PMID: 8946783. 3. Bartus RT, Baker KL, Heiser AD, Sawyer SD, Dean RL, Elliott PJ, Straub JA. Postischemic administration of AK275, a calpain inhibitor, provides substantial protection against focal ischemic brain damage. J Cereb Blood Flow Metab. 1994 Jul;14(4):537-44. PubMed PMID: 8014200.