PAC-1

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TargetMol
Product Code: TAR-T2503
Supplier: TargetMol
CodeSizePrice
TAR-T2503-1mL1 mL * 10 mM (in DMSO)£95.00
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TAR-T2503-5mg5mg£95.00
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Quantity:
TAR-T2503-10mg10mg£107.00
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Quantity:
TAR-T2503-25mg25mg£131.00
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Quantity:
TAR-T2503-50mg50mg£171.00
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TAR-T2503-100mg100mg£252.00
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TAR-T2503-500mg500mg£804.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PAC-1 has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.
CAS:
315183-21-2
Formula:
C23H28N4O2
Molecular Weight:
392.503
Pathway:
Proteases/Proteasome; Apoptosis; Autophagy
Purity:
0.9864
SMILES:
Oc1c(CC=C)cccc1C=NNC(=O)CN1CCN(Cc2ccccc2)CC1
Target:
Apoptosis; Caspase; Autophagy

References

1. Putt KS, et al. Nat Chem Biol, 2006, 2(10), 543-550. 2. Peterson QP, et al. J Mol Biol, 2009, 388(1), 144-158. 3. Seervi M, et al. Cell Death Dis, 2011, 2, e207.