TargetMol

ALC67

Product Code:
 
TAR-T25032
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25032-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T25032-50mg50mg£1,661.00
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Quantity:
TAR-T25032-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ALC67 has a promising anticancer activity that results in the recent discovery of a series of 3-propionyl thiazolidine-4-carboxylic acid ethyl esters as a family of novel antiproliferative agents. It is an activator of the caspase-9 involved apoptotic pathway, which is death receptor-independent.
CAS:
1044255-57-3
Formula:
C15H15NO3S
Molecular Weight:
289.35
Purity:
0.98
SMILES:
CCOC(=O)[C@@H]1CSC(N1C(=O)C#C)c1ccccc1

References

1. Charehsaz M, Onen-Bayram FE, Sipahi H, Buran K, Giri AK, Aydin A. Evaluation of the mutagenic and genotoxic effects of the ALC67 thiazolidine compound in Salmonella strains and human lymphocytes in vitro. Hum Exp Toxicol. 2016 Oct;35(10):1108-15. doi: 10.1177/0960327115621365. Epub 2015 Dec 13. PubMed PMID: 26666987. 2. Onen-Bayram FE, Durmaz I, Scherman D, Herscovici J, Cetin-Atalay R. A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells. Bioorg Med Chem. 2012 Sep 1;20(17):5094-102. doi: 10.1016/j.bmc.2012.07.016. Epub 2012 Jul 20. PubMed PMID: 22867707.