Antioquine
Code | Size | Price |
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TAR-T25100-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Antioquine is a bisbenzyltetrahydroisoquinoline alkaloid from Pseudoxandra sclerocarpa.
CAS:
93767-27-2
Formula:
C37H40N2O6
Molecular Weight:
608.73
Purity:
0.98
SMILES:
CN(CCc1cc(OC)c(O)c(Oc2cc(CCN(C)[C@@H]3Cc4ccc(O)c5C4)c3cc2OC)c16)[C@@H]6Cc7cc5c(OC)cc7
References
1. Ivorra MD, Lugnier C, Catret M, Anselmi E, Cortes D, D'Ocon P. Investigations of the dual contractile/relaxant properties showed by antioquine in rat aorta. Br J Pharmacol. 1993 Jun;109(2):502-9. PubMed PMID: 8358549; PubMed Central PMCID: PMC2175685.
2. D'Ocon MP, Candenas ML, Anselmi E, Zafra-Polo MC, Cortes D. Antioquine: a new bisbenzylisoquinoleine alkaloid with calcium antagonist activity. Arch Int Pharmacodyn Ther. 1989 Jan-Feb;297:205-16. PubMed PMID: 2730236.
3. Catret M, Ivorra MD, D'Oc?n MP, Anselmi E. The 5-HT and alpha-adrenoceptor antagonist effect of four benzylisoquinoline alkaloids on rat aorta. J Pharm Pharmacol. 1998 Mar;50(3):317-22. PubMed PMID: 9600725.
4. Mahiou V, Roblot F, Fournet A, Hocquemiller R. Bisbenzylisoquinoline alkaloids from Guatteria boliviana (Annonaceae). Phytochemistry. 2000 Aug;54(7):709-16. PubMed PMID: 10975506.