Antrimycin
| Code | Size | Price |
|---|
| TAR-T25101-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Antrimycin is an antibiotic.
CAS:
80801-26-9
Formula:
C28H47N9O11
Molecular Weight:
685.736
Purity:
0.98
SMILES:
CCC(C)=C(NC(=O)[C@H](C)NC(=O)[C@@H]1CCC=NN1C(=O)[C@@H](NC(=O)[C@H](C)NC(=O)C(N)(CO)CO)[C@H](C)N)C(=O)N[C@@H](CO)C(O)=O
References
1. Choi EM, Jung WW, Suh KS. Pinacidil protects osteoblastic cells against antimycin A-induced oxidative damage. Mol Med Rep. 2015 Jan;11(1):746-52. doi: 10.3892/mmr.2014.2721. Epub 2014 Oct 21. PubMed PMID: 25334089.
2. Li H, Zhu XL, Yang WC, Yang GF. Comparative kinetics of Qi site inhibitors of cytochrome bc1 complex: picomolar antimycin and micromolar cyazofamid. Chem Biol Drug Des. 2014 Jan;83(1):71-80. doi: 10.1111/cbdd.12199. Epub 2013 Sep 19. PubMed PMID: 23919901.
3. Iglesias DE, Bombicino SS, Valdez LB, Boveris A. Nitric oxide interacts with mitochondrial complex III producing antimycin-like effects. Free Radic Biol Med. 2015 Dec;89:602-13. doi: 10.1016/j.freeradbiomed.2015.08.024. Epub 2015 Oct 9. PubMed PMID: 26456055.
4. Zhang L, Mori T, Zheng Q, Awakawa T, Yan Y, Liu W, Abe I. Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis. Angew Chem Int Ed Engl. 2015 Nov 2;54(45):13462-5. doi: 10.1002/anie.201506899. Epub 2015 Sep 10. PubMed PMID: 26356484.