Aranotin
Code | Size | Price |
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TAR-T25106-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Aranotin is an antiviral compound.
CAS:
19885-51-9
Formula:
C20H18N2O7S2
Molecular Weight:
462.49
Purity:
0.98
SMILES:
CC(=O)O[C@H]1C=COC=C2C[C@@]34SS[C@]5(CC6=COC=C[C@H](O)[C@H]6N5C3=O)C(=O)N4[C@H]12
References
1. Cameron A, Fisher B, Fisk N, Hummel J, White JM, Krenske EH, Rizzacasa MA. Towards the Synthesis of Dihydrooxepino[4,3-b]pyrrole-Containing Natural Products via Cope Rearrangement of Vinyl Pyrrole Epoxides. Org Lett. 2015 Dec 18;17(24):5998-6001. doi: 10.1021/acs.orglett.5b02965. Epub 2015 Dec 2. PubMed PMID: 26629727.
2. Gross U, Nieger M, Br?se S. A unified strategy targeting the thiodiketopiperazine mycotoxins exserohilone, gliotoxin, the epicoccins, the epicorazines, rostratin A and aranotin. Chemistry. 2010 Oct 11;16(38):11624-31. doi: 10.1002/chem.201001169. Epub 2010 Aug 31. PubMed PMID: 20809554.
3. Neuss N, Boeck LD, Brannon DR, Cline JC, DeLong DC, Gorman M, Huckstep LL, Lively DH, Mabe J, Marsh MM, Molloy BB, Nagarajan R, Nelson JD, Stark WM. Aranotin and related metabolites from Arachniotus aureus (Eidam) Schroeter. IV. Fermentation, isolation, structure elucidation, biosynthesis, and antiviral properties. Antimicrob Agents Chemother (Bethesda). 1968;8:213-9. PubMed PMID: 5735362.
4. Nagarajan R, Neuss N, Marsh MM. Aranotin and related metabolites. 3. Configuration and conformation of acetylaranotin. J Am Chem Soc. 1968 Nov 6;90(23):6518-9. PubMed PMID: 5682450.