Bim 21009
| Code | Size | Price |
|---|
| TAR-T25154-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Bim 21009 is an inhibitor of gonadorelin.
CAS:
106881-54-3
Formula:
C74H92ClN17O13
Molecular Weight:
1463.11
Purity:
0.98
SMILES:
C[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(N)=O
References
1. Ezan E, Drieu K, Moreau JP, Dray F. Validation in rat plasma of a direct radioimmunoassay for a luteinizing hormone-releasing hormone antagonist (BIM 21009). J Immunoassay. 1990;11(3):295-309. Erratum in: J Immunoassay 1991;12(1):163-4. PubMed PMID: 2229420.
2. Virolainen JV, Love RJ, Tast A, Peltoniemi OA. Effect of a gonadotrophin-releasing hormone antagonist on luteinising hormone secretion and early pregnancy in gilts. Reprod Fertil Dev. 2003;15(7-8):451-9. PubMed PMID: 15018782.
3. Webley GE, Hodges JK, Given A, Hearn JP. Comparison of the luteolytic action of gonadotrophin-releasing hormone antagonist and cloprostenol, and the ability of human chorionic gonadotrophin and melatonin to override their luteolytic effects in the marmoset monkey. J Endocrinol. 1991 Jan;128(1):121-9. PubMed PMID: 1900320.
4. Hodges JK, Green DI, Cottingham PG, Sauer MJ, Edwards C, Lightman SL. Induction of luteal regression in the marmoset monkey (Callithrix jacchus) by a gonadotrophin-releasing hormone antagonist and the effects on subsequent follicular development. J Reprod Fertil. 1988 Mar;82(2):743-52. PubMed PMID: 3129559.