Cgp 44099
| Code | Size | Price |
|---|
| TAR-T25230-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Cgp 44099 is a potent plasma renin inhibitor from all subprimate species.
CAS:
128856-81-5
Formula:
C69H104N14O13
Molecular Weight:
1337.676
Purity:
0.98
SMILES:
COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(C)C
References
1. Wood JM, Mah SC, Baum HP, de Gasparo M, Cumin F, R?eger H, Nussberger J. Evaluation of a potent inhibitor of subprimate and primate renins. J Pharmacol Exp Ther. 1990 May;253(2):513-7. PubMed PMID: 2110974.
2. Fleetwood G, Boutinet S, Meier M, Wood JM. Involvement of the renin-angiotensin system in ischemic damage and reperfusion arrhythmias in the isolated perfused rat heart. J Cardiovasc Pharmacol. 1991 Mar;17(3):351-6. PubMed PMID: 1711594.
3. Wood JM, Mah SC, Schnell C. Comparison of the acute hypotensive effects of renin inhibition, converting enzyme inhibition, and angiotensin II antagonism in rats. J Cardiovasc Pharmacol. 1990;16 Suppl 4:S60-4. PubMed PMID: 1705630.