Cortivazol
Code | Size | Price |
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TAR-T25271-5mg | 5mg | £1,974.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25271-50mg | 50mg | £3,910.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25271-100mg | 100mg | £5,452.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Cortivazol is an Anti-Inflammatory Drug.
CAS:
1110-40-3
Formula:
C32H38N2O5
Molecular Weight:
530.665
Purity:
0.98
SMILES:
C[C@@H]1C[C@H]2[C@@H]3C=C(C)C4=Cc5c(C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(C)=O)cnn5-c1ccccc1
References
1. Thompson EB, Srivastava D, Johnson BH. Interactions of the phenylpyrazolo steroid cortivazol with glucocorticoid receptors in steroid-sensitive and -resistant human leukemic cells. Cancer Res. 1989 Apr 15;49(8 Suppl):2253s-2258s. PubMed PMID: 2702665.
2. Styczynski J, Kurylak A, Wysocki M. Cytotoxicity of cortivazol in childhood acute lymphoblastic leukemia. Anticancer Res. 2005 May-Jun;25(3B):2253-8. PubMed PMID: 16158972.
3. Yoshikawa N, Makino Y, Okamoto K, Morimoto C, Makino I, Tanaka H. Distinct interaction of cortivazol with the ligand binding domain confers glucocorticoid receptor specificity: cortivazol is a specific ligand for the glucocorticoid receptor. J Biol Chem. 2002 Feb 15;277(7):5529-40. Epub 2001 Dec 10. PubMed PMID: 11741935.
4. Maigne JY. Four cases of coccygeal disk calcification after cortivazol injection. Joint Bone Spine. 2009 Dec;76(6):699-700. doi: 10.1016/j.jbspin.2009.10.005. PubMed PMID: 19945326.