Crilvastatin

TargetMol
Product Code: TAR-T25276
Supplier: TargetMol
CodeSizePrice
TAR-T25276-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T25276-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T25276-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
Crilvastatin is a new inhibitor of hydroxymethylglutaryl-coenzyme A reductase.
CAS:
120551-59-9
Formula:
C14H23NO3
Molecular Weight:
253.342
Purity:
0.98
SMILES:
CC1CC(CC(C)(C)C1)OC(=O)[C@@H]1CCC(=O)N1

References

1. Hajri T, Chanussot F, F?r?zou J, Riottot M, Lafont H, Laruelle C, Lutton C. Reduced cholesterol absorption in hamsters by crilvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. Eur J Pharmacol. 1997 Feb 5;320(1):65-71. PubMed PMID: 9049604. 2. Clerc T, Jomier M, Chautan M, Portugal H, Senft M, Pauli AM, Laruelle C, Morel O, Lafont H, Chanussot F. Mechanisms of action in the liver of crilvastatin, a new hydroxymethylglutaryl-coenzyme A reductase inhibitor. Eur J Pharmacol. 1993 Apr 22;235(1):59-68. PubMed PMID: 8519281. 3. Clerc T, Sbarra V, Diaconescu N, Lafont H, Jadot G, Laruelle C, Chanussot F. Effect of crilvastatin, a new cholesterol lowering agent, on unesterified LDL-cholesterol metabolism into bile salts by rat isolated hepatocytes. Br J Pharmacol. 1995 Feb;114(3):624-31. PubMed PMID: 7735689; PubMed Central PMCID: PMC1510015. 4. Hajri T, F?r?zou J, Laruelle C, Lutton C. Crilvastatin, a new 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, inhibits cholesterol absorption in genetically hypercholesterolemic rats. Eur J Pharmacol. 1995 Nov 14;286(2):131-6. PubMed PMID: 8605949.