Daunosamnyl-daunorubicin
| Code | Size | Price |
|---|
| TAR-T25291-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Daunosamnyl-daunorubicin is used as an antibody conjugate.
CAS:
28008-54-0
Formula:
C33H40N2O12
Molecular Weight:
656.685
Purity:
0.98
SMILES:
COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O[C@H]6C[C@H](N)[C@H](O)[C@H](C)O6)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O
References
1. Gesson JP, Jacquesy JC, Mondon M, Petit P, Renoux B, Andrianomenjanahary S, Dufat-Trinh Van H, Koch M, Michel S, Tillequin F, et al. Prodrugs of anthracyclines for chemotherapy via enzyme-monoclonal antibody conjugates. Anticancer Drug Des. 1994 Oct;9(5):409-23. PubMed PMID: 7945725.
2. Arcamone FM. Sabarubicin. Top Curr Chem. 2008;283:171-89. doi: 10.1007/128_2007_1. PubMed PMID: 23605632.
3. Kaptein SJ, De Burghgraeve T, Froeyen M, Pastorino B, Alen MM, Mondotte JA, Herdewijn P, Jacobs M, de Lamballerie X, Schols D, Gamarnik AV, Sztaricskai F, Neyts J. A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro. Antimicrob Agents Chemother. 2010 Dec;54(12):5269-80. doi: 10.1128/AAC.00686-10. Epub 2010 Sep 13. PubMed PMID: 20837762; PubMed Central PMCID: PMC2981273.
4. Arcamone F, Animati F, Capranico G, Lombardi P, Pratesi G, Manzini S, Supino R, Zunino F. New developments in antitumor anthracyclines. Pharmacol Ther. 1997 Oct-Dec;76(1-3):117-24. Review. PubMed PMID: 9535173.