Demethoxyrapamycin
| Code | Size | Price |
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| TAR-T25305-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Demethoxyrapamycin is a new antifungal antibiotic agent which is co-produced with rapamycin by Streptomyces hygroscopicus.
CAS:
83482-58-0
Formula:
C50H77NO12
Molecular Weight:
884.161
Purity:
0.98
SMILES:
CO[C@@H]1C[C@H](C[C@H](C)[C@@H]2CC(=O)[C@H](C)C=C(C)[C@@H](O)CC(=O)[C@@H](C)C[C@@H](C)C=CC=CC=C(C)[C@H](C[C@@H]3CC[C@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O2)OC)CC[C@@H]1O
References
1. Sehgal SN, Baker H, Eng CP, Singh K, V?zina C. Demethoxyrapamycin (AY-24,668), a new antifungal antibiotic. J Antibiot (Tokyo). 1983 Apr;36(4):351-4. PubMed PMID: 6343327.
2. Eng CP, Sehgal SN, V?zina C. Activity of rapamycin (AY-22,989) against transplanted tumors. J Antibiot (Tokyo). 1984 Oct;37(10):1231-7. PubMed PMID: 6501094.
3. Feng Y, Zhang S, Poloyac S, Strom S, Venkataramanan R. Determination of 13-O-demethyl tacrolimus in human liver microsomal incubates using liquid chromatography-mass spectrometric assay (LC-MS). J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jul 5;821(1):31-7. PubMed PMID: 15897019.