Dihydrohomofolic acid
| Code | Size | Price |
|---|
| TAR-T25332-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Dihydrohomofolic acid is a substrate for dihydrofolate reductase that produces tetrahydro-homo folate which in turn suppresses thymidylate synthetase and then DNA synthesis.
CAS:
14866-11-6
Formula:
C20H23N7O6
Molecular Weight:
457.447
Purity:
0.98
SMILES:
Nc1nc(=O)c2N=C(CCNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2[nH]1
References
1. Mishra LC, Parmar AS, Mead JA. Effect of pretreatment with methotrexate on the reduction of dihydrohomofolic acid in mice. Biochem Pharmacol. 1971 Oct;20(10):2871-8. PubMed PMID: 5114519.