Pitavastatin calcium
Code | Size | Price |
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TAR-T2534-5mg | 5mg | £98.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2534-1mL | 1 mL * 10 mM (in DMSO) | £114.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2534-10mg | 10mg | £114.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2534-25mg | 25mg | £132.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2534-50mg | 50mg | £149.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2534-100mg | 100mg | £208.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T2534-200mg | 200mg | £262.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Pitavastatin is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions.
CAS:
147526-32-7
Formula:
C50H46CaF2N2O8
Molecular Weight:
880.999
Pathway:
Autophagy; Metabolism; Apoptosis
Purity:
0.9971
SMILES:
[Ca++].OC(CC(O)C=Cc1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O.OC(CC(O)C=Cc1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O
Target:
Apoptosis; Mitophagy; Endogenous Metabolite; HMG-CoA Reductase; Autophagy
References
1. Ahmad H, et al. Cardiol Rev, 2010, 18(5):264-267.
2. Martin G, et al. J Clin Invest, 2001, 107(11), 1423-1432.
3. Ohnaka K, et al. Biochem Biophys Res Commun, 2001, 287(2), 337-342.
4. Olsson AG, et al. Cardiovasc Drug Rev. 2002, 20(4):303-28.