TargetMol

Eclazolast

Product Code:
 
TAR-T25360
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25360-1mg1mg£167.00
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TAR-T25360-1mL1 mL * 10 mM (in DMSO)£292.00
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TAR-T25360-5mg5mg£303.00
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TAR-T25360-10mg10mg£424.00
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TAR-T25360-25mg25mg£655.00
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TAR-T25360-50mg50mg£863.00
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TAR-T25360-100mg100mg£1,187.00
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TAR-T25360-500mg500mg£2,295.00
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Further Information

Bioactivity:
Eclazolast is a lipophilic antiallergic compound.
CAS:
80263-73-6
Formula:
C12H12ClNO4
Molecular Weight:
269.68
Purity:
0.98
SMILES:
CCOCCOC(=O)c1nc2cc(Cl)ccc2o1

References

1. Fischer MJ, de Mol NJ. Mechanism of action of the nonlipophilic antiallergic drug eclazolast (REV 2871) in the inhibition of mediator release in a mast cell model. Inflamm Res. 1999 Nov;48(11):569-74. PubMed PMID: 10598012. 2. Coutts SM, Khandwala A, Weinryb I. REV 2871 (CHBZ): a potent antiallergic agent with a novel mechanism of action. II. Studies on the mechanism of action. Biochem Pharmacol. 1987 Mar 1;36(5):673-82. PubMed PMID: 2881546. 3. Khandwala A, Coutts S, Pruss T, Jones H, Neiss E, Weinryb I. REV 2871 (CHBZ): a potent antiallergic agent with a novel mechanism of action. I. Activity profile as an inhibitor of mediator release. Biochem Pharmacol. 1987 Mar 1;36(5):663-72. PubMed PMID: 2435293. 4. Coutts SM, Khandwala A, Shoupe TS, Musser JH, Klunk LJ, Weinryb I. REV 2871 (CHBZ): a novel inhibitor of histamine release. Agents Actions. 1986 Jun;18(3-4):318-24. PubMed PMID: 2428220.