Etarotene
Code | Size | Price |
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TAR-T25393-1mg | 1mg | £278.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25393-5mg | 5mg | £586.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25393-10mg | 10mg | £804.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25393-25mg | 25mg | £1,171.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25393-50mg | 50mg | £1,556.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25393-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T25393-500mg | 500mg | £4,006.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Etarotene is an ethylsulfonyl derivative of arotinoic acid, that has differentiation inducing and potential antineoplastic activities.
CAS:
87719-32-2
Formula:
C25H32O2S
Molecular Weight:
396.59
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
CCS(=O)(=O)c1ccc(C=C(/C)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1
Target:
Tyrosinase
References
1. Zheng ZS, Xue GZ, Prystowsky JH. Regulation of the induction of ornithine decarboxylase in keratinocytes by retinoids. Biochem J. 1995 Jul 1;309 ( Pt 1):159-65. PubMed PMID: 7619051; PubMed Central PMCID: PMC1135814.
2. Xue GZ, Zheng ZS, Chen RZ, Lloyd MB, Prystowsky JH. Phorbol 12-myristate 13-acetate inhibits epidermal growth factor signalling in human keratinocytes, leading to decreased ornithine decarboxylase activity. Biochem J. 1996 Oct 15;319 ( Pt 2):641-8. PubMed PMID: 8912706; PubMed Central PMCID: PMC1217815.
3. Wyss R, Bucheli F. Quantitative analysis of retinoids in biological fluids by high-performance liquid chromatography using column switching. III. Determination of the arotinoid sumarotene and its Z-isomer in human and animal plasma. J Chromatogr. 1992 Apr 15;576(1):111-20. PubMed PMID: 1500445.