Pimozide

TargetMol
Product Code: TAR-T2546
Supplier: TargetMol
CodeSizePrice
TAR-T2546-50mg50mg£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2546-1mL1 mL * 10 mM (in DMSO)£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Pimozide is a diphenylbutylpiperidine derivative and a dopamine antagonist with the antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of the motor and vocal tics and delusions of parasitosis. In addition, this agent antagonizes alpha-adrenergic and 5-HT2 receptors.
CAS:
2062-78-4
Formula:
C28H29F2N3O
Molecular Weight:
461.557
Pathway:
Membrane transporter/Ion channel; Stem Cells; GPCR/G Protein; Neuroscience; JAK/STAT signaling
Purity:
0.9983
SMILES:
Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1
Target:
Potassium Channel; Dopamine Receptor; Adrenergic Receptor; STAT

References

1. Silva MR, et al. Pharmacol Toxicol. 2003 Jul;93(1):42-7.