Griseolic acid
| Code | Size | Price |
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| TAR-T25463-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Griseolic acid is a cyclic adenosine 3',5'-monophosphate phosphodiesterase II inhibitor.
CAS:
79030-08-3
Formula:
C14H13N5O8
Molecular Weight:
379.285
Purity:
0.98
SMILES:
[H][C@@]12O[C@](C=C1O[C@H]([C@H]2O)n1cnc2c(N)ncnc12)([C@@H](O)C(O)=O)C(O)=O
References
1. Takahashi S, Nakagawa F, Kawazoe K, Furukawa Y, Sato S, Tamura C, Naito A. Griseolic acid, an inhibitor of cyclic adenosine 3',5'-monophosphate phosphodiesterase. II. The structure of griseolic acid. J Antibiot (Tokyo). 1985 Jul;38(7):830-4. PubMed PMID: 2993219.
2. Miyakoshi S, Haruyama H, Shioiri T, Takahashi S, Torikata A, Yamazaki M. Biosynthesis of griseolic acids: incorporation of 13C-labeled compounds into griseolic acid A. J Antibiot (Tokyo). 1992 Mar;45(3):394-9. PubMed PMID: 1315729.
3. Murofushi Y, Kimura M, Iijima Y, Yamazaki M, Kaneko M. Studies on griseolic acid derivatives. IV. Synthesis and phosphodiesterase inhibitory activity of acylated derivatives of griseolic acid. Chem Pharm Bull (Tokyo). 1987 Mar;35(3):1036-43. PubMed PMID: 3038344.
4. Murofushi Y, Kimura M, Iijima Y, Yamazaki M, Kaneko M. Studies on griseolic acid derivatives. V. Synthesis and phosphodiesterase inhibitory activity of substituted derivatives of the hydroxy group at the 2'- or 7'-position in griseolic acid. Chem Pharm Bull (Tokyo). 1987 Nov;35(11):4442-53. PubMed PMID: 3442882.