GSK1360707
| Code | Size | Price |
|---|
| TAR-T25467-5mg | 5mg | £1,010.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25467-50mg | 50mg | £1,982.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25467-100mg | 100mg | £2,560.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
GSK1360707 is a selective triple reuptake inhibitor (TRI).
CAS:
1013098-04-8
Formula:
C14H17Cl2NO
Molecular Weight:
286.2
Purity:
0.98
SMILES:
COC[C@@]12C[C@@]1(CCNC2)c1ccc(Cl)c(Cl)c1
References
1. Veeranna KD, Das KK, Baskaran S. One-Pot Synthesis of Cyclopropane-Fused Cyclic Amidines: An Oxidative Carbanion Cyclization. Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16197-16201. doi: 10.1002/anie.201708138. Epub 2017 Nov 27. PubMed PMID: 29083519.
2. Comley RA, Salinas CA, Slifstein M, Petrone M, Marzano C, Bennacef I, Shotbolt P, Van der Aart J, Neve M, Iavarone L, Gomeni R, Laruelle M, Gray FA, Gunn RN, Rabiner EA. Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography. J Pharmacol Exp Ther. 2013 Aug;346(2):311-7. doi: 10.1124/jpet.112.202895. Epub 2013 May 17. PubMed PMID: 23685546.
3. Teller H, F?rstner A. Concise synthesis of the antidepressive drug candidate GSK1360707 by a highly enantioselective gold-catalyzed enyne cycloisomerization reaction. Chemistry. 2011 Jul 4;17(28):7764-7. doi: 10.1002/chem.201101346. Epub 2011 May 26. PubMed PMID: 21618638.
4. Deschamps NM, Elitzin VI, Liu B, Mitchell MB, Sharp MJ, Tabet EA. An enyne cycloisomerization approach to the triple reuptake inhibitor GSK1360707F. J Org Chem. 2011 Jan 21;76(2):712-5. doi: 10.1021/jo102098y. Epub 2010 Dec 21. PubMed PMID: 21174473.