Lamivudine, (+/-)-trans-
| Code | Size | Price |
|---|
| TAR-T25609-5mg | 5mg | £1,332.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25609-50mg | 50mg | £2,625.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25609-100mg | 100mg | £3,524.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lamivudine, (+/-)-trans- is a reverse transcriptase inhibitor and zalcitabine analog. It is used for the treatment of hepatitis B (HBV) and Human Immunodeficiency Virus Type 1 (HIV-1).
CAS:
131086-22-1
Formula:
C8H11N3O3S
Molecular Weight:
229.25
Purity:
0.98
SMILES:
Nc1ccn([C@@H]2CS[C@@H](CO)O2)c(=O)n1
References
1. Heipertz RA Jr, Miller TG, Kelley CM, Delaney WE 4th, Locarnini SA, Isom HC. In vitro study of the effects of precore and lamivudine-resistant mutations on hepatitis B virus replication. J Virol. 2007 Apr;81(7):3068-76. Epub 2007 Jan 10. PubMed PMID: 17215289; PubMed Central PMCID: PMC1866076.
2. Xie Y, Liu Q, Wang CH, Tang CW. [Inhibition of transcription and expression of X gene by lamivudine]. Zhonghua Gan Zang Bing Za Zhi. 2005 Jan;13(1):27-30. Chinese. PubMed PMID: 15670487.
3. Bottecchia M, Ikuta N, Niel C, Araujo NM, O KM, Gomes SA. Lamivudine resistance and other mutations in the polymerase and surface antigen genes of hepatitis B virus associated with a fatal hepatic failure case. J Gastroenterol Hepatol. 2008 Jan;23(1):67-72. doi: 10.1111/j.1440-1746.2007.05238.x. PubMed PMID: 18171343.
4. Luo YY, Tao Y, Cai XF, Zhang WL, Long QX, Guo H, Huang AL, Hu JL. A novel method for nucleos(t)ide analogues susceptibility assay of hepatitis B virus by viral polymerase transcomplementation. Antiviral Res. 2016 Feb;126:99-107. doi: 10.1016/j.antiviral.2015.12.009. Epub 2015 Dec 29. PubMed PMID: 26738784.