Landomycin A
| Code | Size | Price |
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| TAR-T25614-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Landomycin A is a prominent angucycline hexasaccharide antibiotic from Streptomyces sp.
CAS:
130432-93-8
Formula:
C55H74O22
Molecular Weight:
1087.175
Purity:
0.98
SMILES:
C[C@@H]1O[C@@H](CC[C@@H]1O)O[C@@H]1C[C@H](O[C@H]2[C@H](C)O[C@@H](C[C@@H]2O)O[C@@H]2CC[C@@H](O[C@H]3C[C@@H](O)[C@H](C)O[C@@H]3O[C@@H]3[C@@H](C)O[C@H](C[C@H]3O)Oc3ccc(O)c4C(=O)C5=C([C@H](O)Cc6cc(C)cc(O)c56)C(=O)c34)O[C@H]2C)O[C@@H](C)[C@@H]1O
References
1. Yang X, Wang P, Yu B. Tackling the challenges in the total synthesis of landomycin A. Chem Rec. 2013 Feb;13(1):70-84. doi: 10.1002/tcr.201200018. Epub 2013 Feb 6. PubMed PMID: 23389835.
2. Baryal KN, Zhu J. Stereoselective Synthesis of S-Linked Hexasaccharide of Landomycin A via Umpolung S-Glycosylation. Org Lett. 2015 Sep 18;17(18):4530-3. doi: 10.1021/acs.orglett.5b02223. Epub 2015 Sep 3. PubMed PMID: 26334208.
3. Myronovskyi M, Br?tz E, Rosenkr?nzer B, Manderscheid N, Tokovenko B, Rebets Y, Luzhetskyy A. Generation of new compounds through unbalanced transcription of landomycin A cluster. Appl Microbiol Biotechnol. 2016 Nov;100(21):9175-9186. Epub 2016 Jul 13. PubMed PMID: 27412461.
4. Yang X, Fu B, Yu B. Total synthesis of landomycin A, a potent antitumor angucycline antibiotic. J Am Chem Soc. 2011 Aug 17;133(32):12433-5. doi: 10.1021/ja205339p. Epub 2011 Jul 27. PubMed PMID: 21780843.