Lercanidipine. (R)-
| Code | Size | Price |
|---|
| TAR-T25670-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25670-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25670-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lercanidipine. (R)- is an enantiomer of antihypertensive drugs Lercanidipine. Lercanidipine acts by blocking L-type calcium channels, allowing relaxation and opening of blood vessels.
CAS:
185197-70-0
Formula:
C36H41N3O6
Molecular Weight:
611.739
Purity:
0.98
SMILES:
COC(=O)C1=C(C)NC(C)=C([C@@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OC(C)(C)CN(C)CCC(c1ccccc1)c1ccccc1
References
1. Egan CG, Pontremoli R. Role of the fixed-dose combination lercanidipine-enalapril in renal protection. J Nephrol. 2011 Jul-Aug;24(4):428-37. doi: 10.5301/JN.2011.6271. Review. PubMed PMID: 21279953.
2. Kaila HO, Ambasana MA, Thakkar RS, Saravaia HT, Shah AK. A Stability-indicating High Performance Liquid Chromatographic Assay for the Simultaneous Determination of Atenolol and Lercanidipine Hydrochloride in Tablets. Indian J Pharm Sci. 2011 Jul;73(4):376-80. doi: 10.4103/0250-474X.95612. PubMed PMID: 22707819; PubMed Central PMCID: PMC3374551.
3. Soma MR, Natali M, Donetti E, Baetta R, Farina P, Leonardi A, Comparato C, Barberi L, Catapano AL. Effect of lercanidipine and its (R)-enantiomer on atherosclerotic lesions induced in hypercholesterolemic rabbits. Br J Pharmacol. 1998 Dec;125(7):1471-6. PubMed PMID: 9884075; PubMed Central PMCID: PMC1565732.
4. Louren?o LP, Aguiar FA, de Oliveira AR, de Gaitani CM. Quantitative determination of lercanidipine enantiomers in commercial formulations by capillary electrophoresis. J Anal Methods Chem. 2015;2015:294270. doi: 10.1155/2015/294270. Epub 2015 Mar 2. PubMed PMID: 25821632; PubMed Central PMCID: PMC4363879.