Leucine thiorphan
| Code | Size | Price |
|---|
| TAR-T25676-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25676-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25676-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Leucine thiorphan is an inhibitor of enkephalinase.
CAS:
80970-04-3
Formula:
C16H23NO3S
Molecular Weight:
309.42
Purity:
0.98
SMILES:
CC(C)C[C@H](NC(=O)C(CS)Cc1ccccc1)C(O)=O
References
1. Di Maria GU, Katayama M, Borson DB, Nadel JA. Neutral endopeptidase modulates endothelin-1-induced airway smooth muscle contraction in guinea-pig trachea. Regul Pept. 1992 Jun 11;39(2-3):137-45. PubMed PMID: 1438968.
2. Kohrogi H, Nadel JA, Malfroy B, Gorman C, Bridenbaugh R, Patton JS, Borson DB. Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs. J Clin Invest. 1989 Sep;84(3):781-6. PubMed PMID: 2474575; PubMed Central PMCID: PMC329719.
3. Djokic TD, Nadel JA, Dusser DJ, Sekizawa K, Graf PD, Borson DB. Inhibitors of neutral endopeptidase potentiate electrically and capsaicin-induced noncholinergic contraction in guinea pig bronchi. J Pharmacol Exp Ther. 1989 Jan;248(1):7-11. PubMed PMID: 2464061.
4. Djokic TD, Sekizawa K, Borson DB, Nadel JA. Neutral endopeptidase inhibitors potentiate substance P-induced contraction in gut smooth muscle. Am J Physiol. 1989 Jan;256(1 Pt 1):G39-43. PubMed PMID: 2463769.