Levonantradol
| Code | Size | Price |
|---|
| TAR-T25696-5mg | 5mg | £1,167.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Levonantradol is a synthetic cannabinoid analog of dronabinol (Marinol). It shows antiemetic and analgesic effects via activation of CB1 and CB2 cannabinoid receptors.
CAS:
71048-87-8
Formula:
C27H35NO4
Molecular Weight:
437.58
Purity:
0.98
SMILES:
[H][C@@]12CC[C@@H](O)C[C@@]1([H])c1c(N[C@H]2C)cc(O[C@H](C)CCCc2ccccc2)cc1OC(C)=O
References
1. Sheshenev AE, Boltukhina EV, Hii KK. Levonantradol: asymmetric synthesis and structural analysis. Chem Commun (Camb). 2013 May 7;49(35):3685-7. doi: 10.1039/c3cc41388h. Epub 2013 Mar 27. PubMed PMID: 23535893.
2. Young AM, Katz JL, Woods JH. Behavioral effects of levonantradol and nantradol in the rhesus monkey. J Clin Pharmacol. 1981 Aug-Sep;21(S1):348S-360S. PubMed PMID: 6271836.
3. Costa E, Cheney DL, Murray TF. Levonantradol-induced inhibition of acetylcholine turnover in rat hippocampus and striatum. J Clin Pharmacol. 1981 Aug-Sep;21(S1):256S-261S. PubMed PMID: 6271831.
4. Heim ME, Romer W, Queisser W. Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting. J Clin Pharmacol. 1981 Aug-Sep;21(S1):86S-89S. PubMed PMID: 7298877.