Levovirin
| Code | Size | Price |
|---|
| TAR-T25702-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin. Levovirin has similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.
CAS:
206269-27-4
Formula:
C8H12N4O5
Molecular Weight:
244.207
Purity:
0.98
SMILES:
NC(=O)c1ncn(n1)[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O
References
1. Huang Y, Ostrowitzki S, Hill G, Navarro M, Berger N, Kopeck P, Mau CI, Alfredson T, Lal R. Single- and multiple-dose pharmacokinetics of levovirin valinate hydrochloride (R1518) in healthy volunteers. J Clin Pharmacol. 2005 May;45(5):578-88. PubMed PMID: 15831782.
2. Fang C, Srivastava P, Lin CC. Effect of ribavirin, levovirin and viramidine on liver toxicological gene expression in rats. J Appl Toxicol. 2003 Nov-Dec;23(6):453-9. PubMed PMID: 14635270.
3. Lin CC, Luu T, Lourenco D, Yeh LT, Lau JY. Absorption, pharmacokinetics and excretion of levovirin in rats, dogs and cynomolgus monkeys. J Antimicrob Chemother. 2003 Jan;51(1):93-9. PubMed PMID: 12493792.
4. Watson J. Prospects for hepatitis C virus therapeutics: levovirin and viramidine as improved derivatives of ribavirin. Curr Opin Investig Drugs. 2002 May;3(5):680-3. Review. PubMed PMID: 12090539.