Linearol
| Code | Size | Price |
|---|
| TAR-T25735-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Linearol is a diterpene found in Sideritis L. spp. (Lamiaceae) with a broad range of demonstrated properties including antioxidant, anti-inflammatory, and anti-apoptotic activities.
CAS:
37720-82-4
Formula:
C22H34O4
Molecular Weight:
362.51
Purity:
0.98
SMILES:
CC(=O)OC[C@@]1(C)[C@H](O)CC[C@@]2(C)[C@@H]3CC[C@H]4C[C@]3(CC4=C)[C@@H](O)CC12
References
1. Gonz?lez-Burgos E, Duarte AI, Carretero ME, Moreira PI, G?mez-Serranillos MP. Kaurane diterpenes as mitochondrial alterations preventive agents under experimental oxidative stress conditions. Pharm Biol. 2016;54(4):705-11. doi: 10.3109/13880209.2015.1072829. Epub 2015 Oct 1. PubMed PMID: 26427521.
2. Gonz?lez-Burgos E, Carretero ME, G?mez-Serranillos MP. Involvement of Nrf2 signaling pathway in the neuroprotective activity of natural kaurane diterpenes. Neuroscience. 2013 Feb 12;231:400-12. doi: 10.1016/j.neuroscience.2012.10.018. Epub 2012 Oct 16. Erratum in: Neuroscience. 2014 Jun6;269():131. PubMed PMID: 23079631.
3. Gonz?lez-Burgos E, Carretero ME, G?mez-Serranillos MP. Kaurane diterpenes from Sideritis spp. exert a cytoprotective effect against oxidative injury that is associated with modulation of the Nrf2 system. Phytochemistry. 2013 Sep;93:116-23. doi: 10.1016/j.phytochem.2013.03.017. Epub 2013 May 2. PubMed PMID: 23642391.
4. Bruno M, Rosselli S, Pibiri I, Kilgore N, Lee KH. Anti-HIV agents derived from the ent-kaurane diterpenoid linearol. J Nat Prod. 2002 Nov;65(11):1594-7. PubMed PMID: 12444682.