Liriodenine methiodide
| Code | Size | Price |
|---|
| TAR-T25743-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25743-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25743-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Liriodenine methiodide shows antibacterial and antifungal activity against several microorganisms.
CAS:
55974-07-7
Formula:
C18H12INO3
Molecular Weight:
417.202
Purity:
0.98
SMILES:
[I-].C[n+]1ccc2cc3OCOc3c3-c4ccccc4C(=O)c1c23
References
1. Hufford CD, Sharma AS, Oguntimein BO. Antibacterial and antifungal activity of liriodenine and related oxoaporphine alkaloids. J Pharm Sci. 1980 Oct;69(10):1180-3. PubMed PMID: 7420287.
2. Clark AM, Watson ES, Ashfaq MK, Hufford CD. In vivo efficacy of antifungal oxoaporphine alkaloids in experimental disseminated candidiasis. Pharm Res. 1987 Dec;4(6):495-8. PubMed PMID: 3508563.
3. Pabuccuoglu V, Rozwadowska MD, Brossi A, Clark A, Hufford CD, George C, Flippen-Anderson JL. Oxoaporphine alkaloids: conversion of lysicamine into liriodendronine and its 2-O-methyl ether, and antifungal activity. Arch Pharm (Weinheim). 1991 Jan;324(1):29-33. PubMed PMID: 2043039.
4. Tripathi SK, Xu T, Feng Q, Avula B, Shi X, Pan X, Mask MM, Baerson SR, Jacob MR, Ravu RR, Khan SI, Li XC, Khan IA, Clark AM, Agarwal AK. Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis. J Biol Chem. 2017 Oct 6;292(40):16578-16593. doi: 10.1074/jbc.M117.781773. Epub 2017 Aug 18. PubMed PMID: 28821607; PubMed Central PMCID: PMC5633121.