Lorcainide hydrochloride
| Code | Size | Price |
|---|
| TAR-T25757-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25757-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25757-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lorcainide hydrochloride is an antiarrhythmic drug with local anesthetic activity. The antiarrhythmic actions of lorcainide are mediated by an impairment of fast sodium conductance. Lorcainide appears effective in suppressing reentry phenomena and ectopic pacemaker activity, especially in the ventricles.
CAS:
58934-46-6
Formula:
C22H28Cl2N2O
Molecular Weight:
407.38
Purity:
0.98
SMILES:
Cl.CC(C)N1CCC(CC1)N(C(=O)Cc1ccccc1)c1ccc(Cl)cc1
References
1. Luo X, Zeng FD. [HPLC method for determination of lorcainide hydrochloride in human serum]. Yao Xue Xue Bao. 1995;30(8):605-9. Chinese. PubMed PMID: 8571780.
2. Somberg JC, Laux B, Wynn J, Keefe D, Miura DS. Lorcainide therapy in a cardiac arrest population. Am Heart J. 1986 Apr;111(4):648-53. PubMed PMID: 3953387.
3. Lauwers WF, Meuldermans WE, Bracke JO. Mass spectral investigation of the metabolites of lorcainide in man. Eur J Drug Metab Pharmacokinet. 1983 Oct-Dec;8(4):351-62. PubMed PMID: 6673972.
4. Shita A, Bernard R, Mostinckx R, Debacker M. Haemodynamic reactions after intravenous injection of lorcainide hydrochloride in acute myocardial infarction. Eur J Cardiol. 1981;12(5):237-42. PubMed PMID: 7250167.