LY52
| Code | Size | Price |
|---|
| TAR-T25765-5mg | 5mg | £1,091.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25765-50mg | 50mg | £2,143.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25765-100mg | 100mg | £2,801.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.
CAS:
769970-91-4
Formula:
C22H24N4O6
Molecular Weight:
440.456
Purity:
0.98
SMILES:
COc1ccc(C=CC(=O)N2C[C@H](C[C@H]2C(=O)NO)NC(=O)c2cccnc2)cc1OC
References
1. Zhang H, Li X, Wang X, Xu W, Zhang J. Sulfonyl phosphonic 1,4-dithia-7-azaspiro[4,4]nonane derivatives as matrix metalloproteinase inhibitors: Synthesis, a docking study, and biological evaluation. Drug Discov Ther. 2017;11(3):118-125. doi: 10.5582/ddt.2017.01016. PubMed PMID: 28757512.
2. Yang L, Wang P, Wu JF, Yang LM, Wang RR, Pang W, Li YG, Shen YM, Zheng YT, Li X. Design, synthesis and anti-HIV-1 evaluation of hydrazide-based peptidomimetics as selective gelatinase inhibitors. Bioorg Med Chem. 2016 May 1;24(9):2125-36. doi: 10.1016/j.bmc.2016.03.043. Epub 2016 Mar 26. PubMed PMID: 27039251.
3. Zhang J, Li X, Jiang Y, Feng J, Li X, Zhang Y, Xu W. Design, synthesis and preliminary evaluation of ?-sulfonyl ?-(glycinyl-amino)proline peptidomimetics as matrix metalloproteinase inhibitors. Bioorg Med Chem. 2014 Jun 1;22(11):3055-64. doi: 10.1016/j.bmc.2013.12.025. Epub 2013 Dec 21. PubMed PMID: 24755524.
4. Shi L, Wang Q, Wang H, Zhou H, Li Y, Li X. Sulphonamide 1,4-dithia-7-azaspiro[4,4]nonane derivatives as gelatinase A inhibitors. Bioorg Med Chem. 2013 Dec 15;21(24):7752-62. doi: 10.1016/j.bmc.2013.10.016. Epub 2013 Oct 30. PubMed PMID: 24247003.