TargetMol

Melianone

Product Code:
 
TAR-T25789
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T25789-5mg5mg£850.00
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Further Information

Bioactivity:
Melianone exhibits antiviral activity (EC50s: 3-11μM) against three important human pathogens, belonging to the Flaviviridae family, West Nile virus, Dengue virus, and Yellow Fever virus.
CAS:
6553-27-1
Formula:
C30H46O4
Molecular Weight:
470.694
Purity:
0.98
SMILES:
[H][C@]12CC[C@@]3(C)[C@@H](CC[C@]3(C)C1=CC[C@@]1([H])C(C)(C)C(=O)CC[C@]21C)[C@@H]1C[C@@H](O[C@H]1O)[C@H]1OC1(C)C

References

1. Miguita CH, Barbosa Cda S, Hamerski L, Sarmento UC, Nascimento JN, Garcez WS, Garcez FR. 3?-O-tigloylmelianol from Guarea kunthiana: a new potential agent to control Rhipicephalus (Boophilus) microplus, a cattle tick of veterinary significance. Molecules. 2014 Dec 23;20(1):111-26. doi: 10.3390/molecules20010111. PubMed PMID: 25546624. 2. Vieira IJ, Azevedo Ode A, de Souza JJ, Braz-Filho R, Gon?alves Mdos S, de Ara?jo MF. Hirtinone, a Novel cycloartane-type triterpene and other compounds from Trichilia hirta L. (Meliaceae). Molecules. 2013 Feb 26;18(3):2589-97. doi: 10.3390/molecules18032589. PubMed PMID: 23442935. 3. Sanna G, Madeddu S, Giliberti G, Ntalli NG, Cottiglia F, De Logu A, Agus E, Caboni P. Limonoids from Melia azedarach Fruits as Inhibitors of Flaviviruses and Mycobacterium tubercolosis. PLoS One. 2015 Oct 20;10(10):e0141272. doi: 10.1371/journal.pone.0141272. eCollection 2015. PubMed PMID: 26485025; PubMed Central PMCID: PMC4612778. 4. Ntalli NG, Cottiglia F, Bueno CA, Alch? LE, Leonti M, Vargiu S, Bifulco E, Menkissoglu-Spiroudi U, Caboni P. Cytotoxic tirucallane triterpenoids from Melia azedarach fruits. Molecules. 2010 Aug 27;15(9):5866-77. doi: 10.3390/molecules15095866. PubMed PMID: 20802401.