Mesoxalic acid

TargetMol
Product Code: TAR-T25792
Supplier: TargetMol
CodeSizePrice
TAR-T25792-5mg5mg£850.00
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Quantity:
TAR-T25792-50mg50mg£1,661.00
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Quantity:
TAR-T25792-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Mesoxalic acid is a dicarboxylic acid and a ketonic acid which blocks RT translocation.
CAS:
473-90-5
Formula:
C3H2O5
Molecular Weight:
118.044
Purity:
0.98
SMILES:
OC(=O)C(=O)C(O)=O

References

1. Bernatchez JA, Paul R, Tchesnokov EP, Ngure M, Beilhartz GL, Berghuis AM, Lavoie R, Li L, Auger A, Melnyk RA, Grobler JA, Miller MD, Hazuda DJ, Hecht SM, G?tte M. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. J Biol Chem. 2015 Jan 16;290(3):1474-84. doi: 10.1074/jbc.M114.614305. Epub 2014 Oct 29. PubMed PMID: 25355312; PubMed Central PMCID: PMC4340395. 2. Furrow SD, Aurentz DJ. Reactions of iodomalonic acid, diiodomalonic acid, and other organics in the Briggs-Rauscher oscillating system. J Phys Chem A. 2010 Feb 25;114(7):2526-33. doi: 10.1021/jp911492f. PubMed PMID: 20121222. 3. Davis WR, Tomsho J, Nikam S, Cook EM, Somand D, Peliska JA. Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid. Biochemistry. 2000 Nov 21;39(46):14279-91. PubMed PMID: 11087377. 4. BOWNE SW Jr, SRB AM. Tartaric acid metabolism of Neurospora crassa. Science. 1959 Aug 21;130(3373):455-6. PubMed PMID: 13675775.